Literature summary extracted from
Morcos, M.W.; Al-Jallad, H.; Li, J.; Farquharson, C.; Millan, J.L.; Hamdy, R.C.; Murshed, M.
PHOSPHO1 is essential for normal bone fracture healing an animal study (2018), Bone Joint Res., 7, 397-405 .
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
3.1.3.75 |
Mus musculus |
Q8R2H9 |
- |
- |
Source Tissue
EC Number |
Source Tissue |
Comment |
Organism |
Textmining |
---|
General Information
EC Number |
General Information |
Comment |
Organism |
---|
3.1.3.75 |
physiological function |
calli of Phospho1-/- mice display a mild reduction of bone volume and an increase in trabecular number and a decrease in trabecular thickness and separation. There is a marked increase of osteoid volume over bone volume in the Phospho1-/- callus. Phospho1-/- fractured bone is more elastic than the wild-type bone |
Mus musculus |